Clincial Trials Laboratory Technician- 12 Month Fixed Term
£23,000 - £25,000
This role is in the Laboratory of Queen Anne Street Clinical Trials (QASCT) which is situated at the Queen Anne St. Medical Centre in Central London.
The QASCT Laboratory is dedicated to formally evaluate the mechanisms of inflammation in general and specifically in respiratory disease (asthma, allergy, COPD). The clinical trials unit conducts studies to evaluate and determine the potential of new therapeutic agents in asthma, allergy and COPD, and also in urology and gastro-enterology. The laboratory will also develop novel biomarkers and evaluate surrogate biomarkers of inflammation. Facilities are available for Phase I, Phase II and Phase III clinical testing of new drugs in these areas. The unit has consolidated its expertise and experience and has a proven track record in performing clinically based pharmacological research to the highest international standards.
1. To assist and perform with general laboratory duties to contribute to providing an effective and efficient laboratory service
a) To comply with the requirements set out in the QASCT Laboratory Policy.
b) To assist the other laboratory staff in the day to day running of the lab facility.
c) To ensure the sample management procedures are carried out as per QASCT Lab SOPs.
d) To ensure that samples are processed, stored and destroyed appropriately according to the study protocol, analytical plan and GCP/GCLP requirements.
e) To ensure processes and procedures performed are documented fully and records are maintained to a high standard.
f) To ensure the laboratory equipment is maintained and calibrated according to QASCTLaboratory SOPs
g) To ensure that laboratory resources are sourced cost effectively.
h) To maintain and promote high standards of infection control practice.
2. To assist with the implementation of effective archiving systems within the Laboratory
a) To ensure records are maintained and managed to a high standard that adhere to GCP/GCLP requirements
b) To assist with the development and management of archive databases and transportation records
c) To report system failures to senior members of the laboratory team and contribute to problem solving solutions
3. To assist with general administrative duties within the Laboratory
a) To assist with general administrative duties within the laboratory
b) To assist with data QC procedures and data filing within the laboratory
c) To assist with stock taking and ordering of goods/services as and when required.
1. Teamwork & Innovation
a) To exhibit a high standard of communication and interpersonal skills within the
b) To actively contribute to the development of the team by sharing ideas and initiatives
d) To report conflicts and problems to the department manager as they may arise
2. Management of Information
a) To ensure that participant’s confidentiality is observed at all times.
b) To ensure that records are maintained in accordance with local policies.
3. Marketing & I.T.
a) To exhibit excellent I.T skills with a good knowledge of Word, Excel and PowerPoint.
b) To participate in the positive marketing of the clinical trials unit.
4. Personal Development and Training
a) To participate in house education programmes as appropriate
b) To successfully complete induction and orientation programme
c) Comply with units standard operating procedures and policies
d) To demonstrate continuing professional development which reflects the needs of the post holder and the unit
This document is not intended to be an exhaustive list of duties and should be regarded as a broad description of the post. Alterations to this document may take place from time to time as the responsibilities and requirements of the post-holder develop. This document reflects the core activities of the role and as the Laboratory and the post holder develop, there will inevitably be changes in the emphasis of duties. It is expected that the post holder will recognise this and adopt a flexible approach to work and be willing to participate in training. If changes to the job become significant, the Medical Director, Director of Clinical Research and the post holder should review the job description formally. During busy periods within the unit the Laboratory team may be required to adopt a shift pattern, details of these patterns will be openly discussed amongst the laboratory team to ensure that shifts are fairly allocated.
Information of a confidential nature must be kept strictly confidential and should never be disclosed either inside or outside work. It should be noted that breach of confidentiality is a serious offence, which may lead to dismissal.
Training and Education:
QASCT recognises the importance of training in achieving its objective of pursuing excellence in teaching, research and clinical practice through the activities of its staff. We are committed to providing training for all members of staff so that they can perform their jobs effectively and offering them opportunities for further development.
PERSON SPECIFICATION – Laboratory Technician
- 5 GCSE’s including Maths and English or equivalent NVQ.
- BSc Biology or Analytical degree
- Experience of managing confidential administration systems
- Accuracy in documentation of data and effective time management skills
- Experience of processing lab Samples
- Experience of non supervised Lab activities
- Computer literacy for presentation of data, such as MS Word, MS Excel, PowerPoint and email
- The ability and confidence to liaise with colleagues
- Ability to work under sporadic pressure
- Excellent interpersonal and communication skills
- Good negotiation skills to ensure effective value for money
- Strong organisational skills and attention to detail
- The ability and confidence to liaise with colleagues
- Flexibility to work a) under detailed instruction and b) independent of supervision
- Approachable manner and team based attitude
- Punctual timekeeping
- Experience in processing Sputum and bronchial and nasal lavage
- Knowledge of GCP and GCLP
- Knowledge of respiratory disease
This laboratory role is based within the clinical trials unit of Queen Anne Street Medical Centre (QASMC)
QASMC is dedicated to formally evaluate the mechanisms of inflammation in general and specifically in respiratory disease (asthma, allergy, COPD). The clinical trials unit conducts studies to evaluate and determine the potential of new therapeutic agents in asthma, allergy and COPD, and also in urology and gastro-enterology. The laboratory will also develop novel biomarkers and evaluate surrogate biomarkers of inflammation. Facilities are available for Phase I, Phase II and Phase III clinical testing of new drugs in these areas. The unit has consolidated its expertise and experience and has a proven track record in performing clinically based pharmacological research to the highest international standards.
Clinical / Laboratory Research
- To comply with the requirements set out in the QASMC Laboratory Policy.
- To carry out research procedures according to QASMC requirements as appropriate and to follow the Standard Operating Procedures of the unit.
- To carry out research in line with the ICH-GCP, GCLP, national and international guidelines.
- To be aware of Good Clinical Laboratory Practice (ICH-GCP) and current legislation on clinical trials.
- To have a working knowledge of equipment used and maintained within the Laboratory.
- To be able to set up Laboratory equipment and materials following protocol requirements.
- Pro-actively and independently assess compliance of the clinical research activities with current standards of MHRA, other relevant regulations and QASMC requirements.
- To ensure processes and procedures performed are fully documented and records maintained in line with GCP/GCLP requirements.
- To have an understanding and / or experience of the following:
- Processing biological samples (including but not limited to blood, sputum, nasal samples, tissue samples, urine)
- ELISA / Luminex assays
- Flow Cytometry
- Differential cell counts
- To assist and perform with general laboratory duties to contribute to providing an effective and efficient laboratory service, including equipment maintenance and calibration.
- To ensure that samples are processed, stored and destroyed appropriately according to the study protocol, analytical plan, QASMC SOPs and GCP/GCLP guidelines
- To promote good relationships with clients by providing a high quality service and delivering a quality product that meets the required protocol specifications.
- To represent, from time to time, QASMC in promotional or pre-study activities.
- To establish good lines of communications with all colleagues.
- To co-ordinate with the Clinical Trials Unit staff to ensure work can be completed expeditiously.
- To inform the Director of Clinical Research of any current or foreseeable problems.
- Must be able to work independently.
- Must be able to work in a multi-disciplinary team.
Personal Development and Training
- To participate in any in-house education programme as appropriate.
- To demonstrate continuing professional development that reflects the needs of the post-holder and the unit.
- Comply with the relevant polices and SOPs of the Queen Anne Street Medical Centre.
- To report accidents or untoward occurrences that arises within the unit to the Director of Clinical Research.
- To ensure standards of hygiene, cleanliness and care of the Laboratory meet the high standards expected within the Facility.
- To ensure that only approved staff and guests enter the unit.
- BSc Biology or Analytical degree
- Minimum 2 years laboratory experience
- Experience of processing laboratory samples
- Knowledge of ICH-GCP and GCLP
- Experience of unsupervised laboratory activities
- The ability to present and represent at all times the department/hospital in a professional manner
- Excellent interpersonal skills at all levels of an organisation
- Ability to cope with competing priorities and to deliver on time
- Advanced computer literacy for presentation of data, using Office Software.
- Approachable manner and team-based attitude
- Flexible attitude to work and a willingness to work flexible hours
- Punctual timekeeping
We are currently expanding our pool of Bank Laboratory Technicians to support our Clinical Research team during busy periods.
Queen Anne Street Medical Centre is private hospital near Harley Street, London with a dedicated clinical trials department conducting a range of clinical trials across multiple indications. During busy periods of clinical activity we call upon members of bank team to support the studies.
The laboratory processes samples taken from clinical research patients and prepares them for shipment to central laboratories for analysis. Therefore experience in a processing laboratory is essential with some analytical skills desirable. Day, evening and night shifts are available, flexibility is essential.
For more information please contact the Director of Clinical Research (Thomas.Morrish@qasmc.com).
Please submit your CV and availability by clicking 'Apply'.
Applications are invited for Clinical Research Nurses to join us in the Clinical Trials Unit within the Queen Anne Street Medical Centre. This position is for bank staff only, successful applicants will be placed on our bank staff list to assist with Clinical Trials in busy periods.
Our vibrant research team brings both expertise and an interactive approach in the early development of new medicines for respiratory disease at our central London private hospital.
We are looking for a registered nurse with excellent clinical skills to join our dedicated and enthusiastic clinical team. This would be a superb opportunity for the right candidate to expand their skills and develop their career within a clinical research setting.
The role will involve playing a key role in the clinical research team carrying out all aspects of the clinical research studies within the department. The role will involve:
Carrying out Phase I-III clinical trials according to protocol
Full involvement in all clinical procedures
Interaction with a variable clinical trial team including other on-site departments
Knowledge of ICH – GCP principles is highly desirable.
Flexibility over working hours is essential- working hours may include day shifts, evening shifts and overnights.
Please send your CV and availability to the Clinical Research Manager by clicking 'Apply'.